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JCM | Free Full-Text | PARP Inhibitors as a Therapeutic Agent for  Homologous Recombination Deficiency in Breast Cancers
JCM | Free Full-Text | PARP Inhibitors as a Therapeutic Agent for Homologous Recombination Deficiency in Breast Cancers

Piet Ost on X: "How does PARPinhibitors work? By Kim Chi. Not all molecules  do PARP trapping in the same way. #APCCC19 https://t.co/1h7XWt8uSl" / X
Piet Ost on X: "How does PARPinhibitors work? By Kim Chi. Not all molecules do PARP trapping in the same way. #APCCC19 https://t.co/1h7XWt8uSl" / X

Avoid the trap: Targeting PARP1 beyond human malignancy - ScienceDirect
Avoid the trap: Targeting PARP1 beyond human malignancy - ScienceDirect

An Overview of PARP Inhibitors for the Treatment of Breast Cancer |  Targeted Oncology
An Overview of PARP Inhibitors for the Treatment of Breast Cancer | Targeted Oncology

Rationale for combination therapies with poly(ADP-ribose) polymerase... |  Download Scientific Diagram
Rationale for combination therapies with poly(ADP-ribose) polymerase... | Download Scientific Diagram

Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of  action | Science Translational Medicine
Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action | Science Translational Medicine

Trapping PARP-DNA complexes - anti-cancer drug screening - Tebubio's blog
Trapping PARP-DNA complexes - anti-cancer drug screening - Tebubio's blog

Mechanism of action of poly (ADP) ribose polymerase (PARP) inhibitors.... |  Download Scientific Diagram
Mechanism of action of poly (ADP) ribose polymerase (PARP) inhibitors.... | Download Scientific Diagram

Cancers | Free Full-Text | PARP Inhibitors in Melanoma—An Expanding  Therapeutic Option?
Cancers | Free Full-Text | PARP Inhibitors in Melanoma—An Expanding Therapeutic Option?

PARP inhibitors: enhancing efficacy through rational combinations | British  Journal of Cancer
PARP inhibitors: enhancing efficacy through rational combinations | British Journal of Cancer

Inhibitors of PARP: Number crunching and structure gazing | PNAS
Inhibitors of PARP: Number crunching and structure gazing | PNAS

Avoid the trap: Targeting PARP1 beyond human malignancy
Avoid the trap: Targeting PARP1 beyond human malignancy

Alternate therapeutic pathways for PARP inhibitors and potential mechanisms  of resistance | Experimental & Molecular Medicine
Alternate therapeutic pathways for PARP inhibitors and potential mechanisms of resistance | Experimental & Molecular Medicine

Biomarkers beyond BRCA: promising combinatorial treatment strategies in  overcoming resistance to PARP inhibitors | Journal of Biomedical Science |  Full Text
Biomarkers beyond BRCA: promising combinatorial treatment strategies in overcoming resistance to PARP inhibitors | Journal of Biomedical Science | Full Text

PARP inhibitor BMN-673 induced apoptosis by trapping PARP-1 and inhibiting  base excision repair via modulation of pol-β in chromatin of breast cancer  cells - ScienceDirect
PARP inhibitor BMN-673 induced apoptosis by trapping PARP-1 and inhibiting base excision repair via modulation of pol-β in chromatin of breast cancer cells - ScienceDirect

PARP1 and PARP trapping with PARP inhibitors. (A) PARP1 structural... |  Download Scientific Diagram
PARP1 and PARP trapping with PARP inhibitors. (A) PARP1 structural... | Download Scientific Diagram

JCI - The evolving landscape of predictive biomarkers of response to PARP  inhibitors
JCI - The evolving landscape of predictive biomarkers of response to PARP inhibitors

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair -  ScienceDirect
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair - ScienceDirect

Frontiers | Perspectives on PARP Inhibitor Combinations for Ovarian Cancer
Frontiers | Perspectives on PARP Inhibitor Combinations for Ovarian Cancer

PARP/PARPTrap™ Screening and Profiling Services
PARP/PARPTrap™ Screening and Profiling Services

Clinical PARP inhibitors (PARPis) and determinants of response and... |  Download Scientific Diagram
Clinical PARP inhibitors (PARPis) and determinants of response and... | Download Scientific Diagram

Setting a Trap for PARP1 and PARP2
Setting a Trap for PARP1 and PARP2

Setting Better Traps for PARP Inhibitors | The Scientist Magazine®
Setting Better Traps for PARP Inhibitors | The Scientist Magazine®

Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance:  Trends in Molecular Medicine
Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance: Trends in Molecular Medicine

PARPtrap™ Assay Kit for PARP1
PARPtrap™ Assay Kit for PARP1

Classification of PARP Inhibitors Based on PARP Trapping and Catalytic  Inhibition, and Rationale for Combinations with Topoisomerase I Inhibitors  and Alkylating Agents | SpringerLink
Classification of PARP Inhibitors Based on PARP Trapping and Catalytic Inhibition, and Rationale for Combinations with Topoisomerase I Inhibitors and Alkylating Agents | SpringerLink

Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of  action | Science Translational Medicine
Laying a trap to kill cancer cells: PARP inhibitors and their mechanisms of action | Science Translational Medicine